Trading has now begun on Facebook after a bit of a hiccup with NASDAQ, and while the numbers are nowhere near the heady heights?of $70-$100 that some people were murmuring earlier, the $42.05 opening figure is still 10 percent higher than the $38-per-share price set by Facebook yesterday. At the time of this writing, it is trading a bit lower, at $40.75, which gives the company about a $111 billion valuation. In Facebook's S-1, the company listed how many shares main players were set to sell at listing time. Based on the originally sale price of $38 and then Facebook's current price at $40.75, here are how the values are coming out. The first number is the value of the shares they sold, and the second is the value of their remaining stake in the company:
Sunday, May 20, 2012
Facebook?s Key Executives And Shareholders: What Is Everyone Worth?
Trading has now begun on Facebook after a bit of a hiccup with NASDAQ, and while the numbers are nowhere near the heady heights?of $70-$100 that some people were murmuring earlier, the $42.05 opening figure is still 10 percent higher than the $38-per-share price set by Facebook yesterday. At the time of this writing, it is trading a bit lower, at $40.75, which gives the company about a $111 billion valuation. In Facebook's S-1, the company listed how many shares main players were set to sell at listing time. Based on the originally sale price of $38 and then Facebook's current price at $40.75, here are how the values are coming out. The first number is the value of the shares they sold, and the second is the value of their remaining stake in the company:
Computers Abort Private Rocket Launching to Space Station
[unable to retrieve full-text content]The launch of a rocket owned by the private company SpaceX and carrying cargo for the International Space Station was aborted at the last second early Saturday.
Jack White attempts record for most metaphors
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Saturday, May 19, 2012
Video: Facebook Barely Holds IPO Price
Reacting to Facebook's first day of trading and forecasting its performance next week, with Russ Koesterich, BlackRock's iShares and the "Closing Bell" crew.
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Our Pilgrimage
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Video: A cell's first steps: Building a model to explain how cells grow
Friday, May 18, 2012
A collaboration between Lehigh University physicists and University of Miami biologists addresses an important fundamental question in basic cell biology: How do living cells figure out when and where to grow?
The teams of Assistant Professor Dimitrios Vavylonis and Associate Professor Fulvia Verde discovered that protein Cdc42 oscillates throughout yeast cells, precipitating a ballet of proteins that change its polarity. By changing polarity, Cdc42 regulates shape, structure and function in yeast cells, starting the growth process by clustering in an area of the cellular membrane. The oscillatory mechanism they found may be a general strategy among all self-organizing biological systems, not just simple yeast.
"The research is fundamental because it provides science with an important answer to how a living cell controls its growth process," said Vavylonis. "Knowing how this particular protein controls growth could in the long run affect the search for drugs to control cell growth for tissue regeneration, organ development, and explain how neurons extend in different directions."
This work indicates how Cdc42 activates bipolar growth only once a minimal cell length has been achieved. At that point, Cdc42 begins to oscillate back and forth through the cell, as the two tips compete for it. Using fluorescent markers to tag each of the many proteins involved, researchers observed the Cdc42 protein oscillate from side to side within a cell, switching sides about every five minutes. The fluctuations provide an adaptable mechanism for cells to control their size and structure in the fast-changing environment within.
The study, Oscillatory Dynamics of Cdc42 GTPase In The Control of Polarized Growth, appears today in the journal Science.
The findings demonstrate just part of the complex process of cell growth and differentiation, but mark how advanced the science of biophysics has become. Only recently has the clear imaging and monitoring of protein activity become possible at the minute sizes and shortened time scales of individual cell maturation.
"Up until now, no one has ever seen the way this protein oscillates back and forth throughout the cell," said Tyler Drake, a Lehigh graduate student and co-author of the paper. "Looking at a simple system like yeast may allow us to understand the principles behind growth in other cells."
This video shows active Cdc42 oscillating through yeast cells.Credit: University of Miami Miller School of Medicine
Vavylonis's research has for years explored the way the cellular cytoskeleton organizes and functions. In collaboration with biologists and computer scientists, his team uses physics to study, analyze, and model the physical properties of these adaptive biological materials.
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Lehigh University: http://www.lehigh.edu
Thanks to Lehigh University for this article.
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